Screening for an infertile couple
Infertility is a disease of the male or female reproductive system defined by the failure to achieve a pregnancy after 12 months or more of regular unprotected sexual intercourse. Reasons for infertility may include genetic factors.
There are two main genetic categories that need to be investigated as they have been implicated in infertility: chromosomal abnormalities and gene damage.
Problems with sperm quantity and quality such as oligospermia, azoospermia, asthenospermia in men or primary and secondary amenorrhoea in women may have a genetic cause.
Genetic testing in couples with reproductive problems (multiple miscarriages, inability to conceive normally, failed assisted reproduction attempts, etc.) is planned based on the clinical genetic evaluation of each couple’s history.
ASTREA HEALTH infertility screening includes:
– Peripheral blood karyotype (G-banded chromosome analysis)
– Molecular screening for thrombophilia in women
– Molecular screening for microdeletions on the Y chromosome in men
– Molecular screening for cystic fibrosis (recommend full screening for cystic fibrosis in men because some cystic fibrosis mutations have been associated with infertility in men)
– Molecular karyotype array CGH of spermatozoa
– Endometrial Microbiome Analysis
– Sperm DNA fragmentation
ASTREA HEALTH offers infertile couples counselling and this infertility genetic screening to identify the genetic cause of their infertility, in order to help them have a child.